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Zanaflex (Tizanidine)

Also known as: Splitz, Tizan, Pramiracetam, Sirdalud, Ternelin 
Zanaflex (Tizanidine) is a skeletal muscle relaxant used to treat muscle spasms associated with multiple sclerosis or spinal cord injuries. It may also be used to treat other conditions as determined by your doctor.
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Prescribing Information for Zanaflex (Tizanidine):

What is Zanaflex (Tizanidine)?

Zanaflex (Tizanidine) is mainly indicated for the treatment of severe muscle spascity when it is associated with severe pathological conditions like multiple sclerosis, injury or pot`s disease of spine which can occur due to any reason.

Zanaflex (Tizanidine) can cause drowsiness. Patient may feel very dull and sleepy after taking this drug. Therefore, you must not operate on heavy machines or should not drive heavy vehicles after taking this drug. You should not take this drug if you have any liver dysfunction.

Your liver function test should be performed before start taking Zanaflex (Tizanidine). If any liver trouble is seen contact your physician instantaly. Liver symptoms include nausea, abdominal pain, yellow color of skin or jaundice you must use it carefully in patients with decreased renal function, kidney disorders, in old people and in children.

Zanaflex (Tizanidine) is contraindicated in patients having severe heart, lung or kidney disease. Patients who have been taking antidepressant drugs like floroxamine or patients on antibiotic prescription should avoid Zanaflex.

This drug is also to be avoided in pregnancy and in breastfeeding mothers. Persons with allergic reaction to galactose or galactose intolerance should also avoid this drug. It is not to be used individuals below 18 years of age. Do not take Zanaflex until your doctor prescribes it. If you have suffered any Allergic reaction with this drug before do not take this drug.

Zanaflex (Tizanidine) is contraindicated in gestating and lactating women. It can pass through placenta and harm the developing fetus. It is recognized to pass through mother`s milk. It can be dangerous for the new born and produce side effects. It you are planning to get conceived stop taking Zanaflex at least 15 days before your plans. Talk to your doctor to learn more about this.

Alcoholic drinks are also to be avoided with Zanaflex (Tizanidine) as it can cause excessive sedation. You must be confident about your conscious before starting taking Zanaflex. Avoid operating on machines or driving vehicles after using this drug.

What should I know about Zanaflex (Tizanidine)?

Zanaflex (Tizanidine) is used to treat severe muscle spasticity occurring because of multiple sclerosis or any severe pathological condition related to spine. It relieves the contraction and tension in muscles of body.

It has tizanidine hydrochloride as main ingredient. Zanaflex belongs to alpha-2 adrenoceptors against class of drugs. It is the major muscle relaxant when severe injuries have occurred. It works by reducing the contraction in muscles. It can block the alpha-2 adrenoceptors in the CNS that is brain and spine in order to reduce the signals being sent from the spinal cord to the muscles.

This will bring down the tension and thus, less pain will be felt. Multiple sclerosis or spinal cord injuries are very painful conditions which are difficult to tolerate. Therefore, patient needs some antispasmodic drugs.

Zanaflex (Tizanidine) is one than and can treat severe spasms in the muscles. This will also reduce the stiffness of the muscles and patients will feel relaxed. Patients will be able to move their muscles in a better way with less pain.

How to use Zanaflex (Tizanidine)?

Zanaflex (Tizanidine) should be taken exactly as prescribed by your doctor and as written on your prescription label. Take it as a whole, don’t break it. Use water to swallow and never combine it with alcohol.

You should not exceed three doses in one day. You must keep a gap of 6-8 hours between every dosage you ingest. Do not overdose or over-medicate yourself. Take it for the duration as prescribed by your physician.

If any severe side effects occur or overdosing is done sick medical advise quickly. Taking Zanaflex tablets with food will increase the absorption of blood. The affect of Zanaflex may decrease without food or empty stomach.

Your medical service provider can change the dosage from time to time. He will tell you if you need capsules or tablets. Don’t take more than three tablets a day as the side effects can be seen particularly liver disorders. Store the drug is cool and dry place.

What can the side effects of Zanaflex (Tizanidine)?

It can cause side effects depending upon the susceptibility, age, sex and livings of an individual. If you experience anything serious after using Zanaflex (Tizanidine), stop your drug and consult your doctor.

Do not take if you have chronic, long running disease. There can mild to moderate side effects. These can be dry month, dullness, sleepiness during work, fatigue, headache, and change in gastrointestinal tract like constipation, diarrhea, pain and cramps in abdomen, vomiting with or without nausea. You may feel light headed, low blood pressure and anxiety on account of Zanaflex.

There can be palpitations or skin rashes. Rare side effects are loss of sleep or insomnia, hallucinations or false perceptions, changes in LFT or liver function test, hepatitis attack and liver failure to know more about the side effects and to know about how to remove side effects refer to your description label.

How Zanaflex (Tizanidine) interacts with other drugs?

Zanaflex (Tizanidine) may interact with other drugs to alter the absorption rate, properties etc. You must be cautions before stacking it with other drugs. Your doctor should know every herbal supplement that you are taking.

Do tell about the over the counter drugs too. It is contraindicated with antidepressant drugs like fluoxamine and with quinolone antibiotics like ciprofloxacin and norfloxacin. If you have been using these drugs you must inform your doctor.

You should not take Zanaflex (Tizanidine) along with cimetidine, anti-arrhythmic. The heart beat can increase or may become abnormal if Zanaflex is combined with beta blockers like propanolol and digoxin. Your blood pressure can reduce and there can be dizziness if Zanaflex (Tizanidine) is taken with antihypertensive drugs. Therefore, you must talk to your doctor before stacking it with any other drug. Drowsiness or sedation may increase with narcotics, alcohol, sleeping tablets, sedating-antihistamine drugs, TCA or tricyclic antidepressant drugs, benzodiazepines and oral contraceptives.

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