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Prescribing Information for Parlodel (Bromocriptine):
What Is Parlodel (Bromocriptine)?
Parlodel, with Parlodel as its generic name, belongs to the drug classification of Dopamine Receptor Agonists. As such, this drug mimics the effects of the neurotransmitter Dopamine which controls different brain and bodily functions. Dopamine naturally occurs in the body and low levels of this neurotransmitter leads to development of Parkinson`s Disease.
One of the main actions of Dopamine is to inhibit the release of Prolactin from the pituitary gland. With low levels of dopamine, production of prolactin becomes unregulated and uncontrolled thus leading to high levels of prolactin. So in effect, Parlodel (Bromocriptine) is used as a drug that mimicks the effect of Dopamine, thus inhibiting the production of Prolactin, as well.
Parlodel (Bromocriptine) is usually taken to treat conditions wherein there is an imbalance in the hormonal levels. One example is hyperprolactinemia wherein there is an excessive amount of prolactin in the blood. This hormonal imbalance is characterized by a decreased pace of sexual development especially obvious in adolescents. For women, amenorrhea may happen which is characterized by missed menstrual periods. Loss of libido, as well as infertility and unexpected breast milk leakage may occur because of this imbalance. For men on the other hand, gynecomastia or enlarged breasts may happen, as well as decreased libido and facial body hair.
These hormonal imbalances may happen due to brain tumors that may mimic the glands which produce prolactin. Parlodel is used in these cases and this drug may be used in conjunction with other treatment modalities like surgery, radiation therapy, and the likes.
Since Parlodel is also a Dopamine agonist, it is also used to treat signs and symptoms of Parkinson\'s Disease such as muscular rigidity, uncontrolled spasms and tremors.
There are also other conditions not mentioned above wherein Bromocriptine is used as a drug of choice.
What To Discuss With My Health Care Provider Before Taking Parlodel (Bromocriptine)?
Since Parlodel (Bromocriptine) has been known to make people drinking this drug feel drowsy and sleepy, it is important to tell your physician if you usually have problems staying awake and alert during daytime. Also, working with heavy machineries or driving may be discouraged while taking this drug so it is also vital to make your physician aware of your occupation.
It is also a must to inform your doctor of some plans to become pregnant while taking this drug. It is a fact that some people take this drug in order to get higher chances of becoming pregnant because it normalizes menstruation, too. Once you have become pregnant, tell your doctor as this drug might be halted.
While Bromocriptine is not classified as detrimental to a growing fetus, this may be dangerous most especially if the pregnant woman becomes hypertensive. Also, in some cases, pregnancies can expand an existing brain tumor.
Thus, if you are taking this drug, but do not have plans of getting pregnant, or avoiding it, it is recommended that you use artificial contraceptives to prevent conception. Also, in the course of treatment, your physician might ask you to do regular pregnancy tests just to make sure you do not get pregnant because otherwise, you might be taking the drug without being aware of the growing fetus inside. After giving birth, taking Parlodel (Bromocriptine) is also not recommended as it interferes with milk production.
Parlodel (Bromocriptine) may also contain lactose so it is important to inform your physician if you have some metabolic problems with lactose such as lactose intolerance, lactase deficiency or glucose-galactose malabsorption.
Important Things You Have To Know About Parlodel (Bromocriptine).
It is important to take note that people taking Parlodel do fall asleep or feel sleepy while doing daytime activities and this drowsy feeling may come off suddenly. It is vital to tell your physician about problems with being drowsy during daytime or similar concerns. If you are taking this medicine and unsure as to how your body will react to this drug, you have to be careful to not do anything heavy that may be dangerous in case you suddenly feel drowsy and sleepy. Driving is also highly discouraged as it may lead to accidents.
Uncontrolled Hypertension, as well as similar diseases like eclampsia (pregnancy induced hypertension), as well as allergy to medicines like Methergine, Ergomar and those in the Ergot Family is a contrainidication to taking Parlodel.
Like other drugs, it is best to confide with your physician other diseases that you are currently being treated for, or diseases which you\'ve had before like Heart Attack, Metabolic Diseases or Disorders, Liver and Kidney Disorders, Gastrointestinal Bleeding or Ulcerations, as well as Mental Disorders.
What Happens If I Miss a Dose or Overdose?
If you remembered missing a dose of Parlodel (Bromocriptine), be sure to take it immediately. However, if the next dose is almost time for you to take, skip the missed dose and also, do not take two doses to compensate for a missed dose.
Overdose symptoms like nausea and vomiting, constipation, hallucination, confusion and fainting must be reported to the physician immediately, otherwise seek for Poison Control assistance.
What To Avoid When Taking Parlodel (Bromocriptine)?
Since Parlodel makes our alertness level decrease, taking alcohol can increase its side effects so it is a must to avoid alcohol and alcohol containing products. Also, when getting up from a lying or sitting position, make sure you do it slowly because it may cause falls and fainting.
How Should I Take Parlodel (Bromocriptine)?
Taking Parlodel should follow whatever instructions your physician has given you since it greatly affects your hormonal levels, especially dopamine and prolactin. Never take this drug in dosages smaller or greater than the prescribed dose. It is also important to take note of the instructions noted in the drug label/ literature.
Since taking this drug might be long term, the doctor might adjust the dosages after some period of time and titrate it according to how your body responds to the drug.
Bromocriptine (Parlodel) should be taken with food at bedtime because it can make a person feel drowsy thus inducing and promoting better sleep. Also, make sure not to skip taking the drug to get the best benefits of the drug.
Regular diagnostic exams of the blood, heart, kidney and liver function may also be done in the course of treatment to make sure that everything is working fine and unaffected. Visiting your physician regularly is also vital.
Parlodel (Bromocriptine) Side Effects.
Allergic reactions to Parlodel may include hives, swelling of the lips, face or throat, difficulty of breathing and restlessness, as well. Seek emergency assistance in these occurence.Serious side effects of Parlodel (Bromocriptine) are the following:
- Drowsiness/ Suddenly falling asleep in the midst of an activity;
- Palpitations, difficulty of breathing;
- Confusions, hallucinations and mental changes;
- Loss of balance and coordination;
- Black or Tarry Stools which may indicate stomach ulceration;
- High Blood Pressure;
The drug also has less serious side effects like minor dizziness, headache, nausea, vomiting, loss of appetite, diarrhea or constipation and other common side effects.
These are a few of the side effects of this drug and still, your physician is most knowledgeable about this issue.
What Other Drugs Will Affect Parlodel (Bromocriptine)?Tell your physician if you are taking the following drugs or anything similar to them:
- Metoclopramide- drugs that prevent dizziness and nausea
- Haloperidol- an antipsychotic drug
- Ergot Medicine (Methergine, Ergotamine, etc)
- Anti Hypertensive Drugs- all types of drugs like Beta Blocker, ACE Inhibitor, Calcium Channel Blockers, Angiotensin Blockers, etc.
- Psychoactive Drugs (drugs used to treat psychiatric disorders)
- Antibiotic or Antifungal Medications
- Statins or cholesterol lowering drugs
- Anti-autoimmune drugs or drugs used to treat post-organ transplant patients
These and more drugs can affect Parlodel (Bromocriptine) but taking these drugs doesn\'t mean that you will not be able to take Parlodel (Bromocriptine) anymore. Just inform your physician that you are taking this drug and he might do some adjustments to the dose or whatever he deems appropriate.
Telling your physician and disclosing helpful information about all the drugs that you have taken or are currently taking is important. Even simple herbal medicines or maintenance vitamins can interact with any drug, and that includes Parlodel. Also keep in mind that once you\'ve started taking Parlodel (Bromocriptine), do not attempt to start taking other medications without the consent or approval of your doctor.
Where Can I Get More Information About Parlodel (Bromocriptine)?
As always, it is best to consult your Physician or Pharmacist for more information about this drug. These people can provide you accurate and legitimate information with regards to all aspects of the drug, whether it be taking the drug, its side effects and adverse effects, alternatives to taking the drug and the like.
Parlodel (Bromocriptine) is a helpful drug especially in treating hyperprolactinemia as well as acromegaly and even in conjunction with other brain tumor treatments. But just like all other drugs, Parlodel (Bromocriptine), too has its limitations which we have to be careful of. Being cautious and at the same time conscious will eventually lead to recovery from the conditions that we are being treated for.