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Fosamax (Alendronate)

Also known as: Osteofos, Ostepos, Resofos, Acide Alendronique, Acido Alendronico, Adronat, Alendronic acid, Alendros, Arendal, Onclast 
Fosamax (Alendronate) is a bisphosphonate used to prevent and treat osteoporosis. It may also be used to treat paget's disease, steroid-induced osteoporosis, and other conditions as determined by your doctor.
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Prescribing Information for Fosamax (Alendronate):

What is Fosamax (Alendronate)?

Fosamax (Alendronate) is part of the medicine classification of Biphosphonates. These drugs affect the cycle of bone formation (osteogenesis) and bone breakdown in the body. Fosamax is responsible for slowing down bone loss while increasing bone mass, thus preventing occurrences of fractures and dislocations.

Fosamax (Alendronate) is widely used among men and women to treat and avoid the occurrence of Osteoporosis caused by either menopausal (women) or long term use of steroids. Fosamax increases bone mass in men who have osteoporosis and also treats another disease called Paget’s Disease of the bone in men and women.

Other medical conditions may also be a ground for Fosamax treatment, though unspecified in this medication guide.

What is important to know about Fosamax (Alendronate)?

Never take Fosamax tablet if you have a difficulty in sitting upright or standing for at least 30 minutes. Fosamax (Alendronate) can also lead to serious problems in the GI tract, most specifically the stomach or esophagus (the structure that connects the mouth and the stomach). Staying upright or standing for at least 30 minutes after taking Fosamax is important.

Take Fosamax (Alendronate) tablet first thing in the morning, most specifically at least 30 minutes before eating, drinking or taking other medicines. This is important to have the drug absorbed fully by the body.

Take Fosamax (Alendronate) with a full glass of water (6-8 ounces). Plain water is the most preferred fluid to accompany taking Fosamax. Mineral water, coffee, tea or any other beverages are not meant to be taken with Fosamax.

It is important to remember that at least 30 minutes after taking the drug; you have to avoid lying down or reclining. You have to maintain an upright or standing position. Never eat or drink anything, except for plain water and do not also take other medications be it OTC or prescribed; that also includes vitamins, minerals, calcium supplements and antacids.

Some people using drugs similar to the effects of Fosamax (Alendronate) experience bone loss in the jaw, a condition called Osteonecrosis of the jaw. Signs and symptoms of this condition includes jaw pain, swelling, numbness of the jaw, teeth loss, gum infection or gingivitis, and also slow healing of the gums after an injury or surgery. People who have cancer or have been treated with chemotherapy, radiation or steroids are most susceptible to developing osteonecrosis of the jaw. Other conditions which may be related to this condition are blood clotting disorders like Hemophilia, Anemia, and a pre-existing dental condition.

If you are scheduled to have any dental work ups (especially surgical procedures), be sure to tell your physician and dentist ahead of time that you are taking Fosamax (Alendronate). You may have to pause from taking the drug for a short time.

Since Fosamax (Alendronate) is a treatment for Osteoporosis, it is important to consider that it is just a part of a group of treatment options, which among others include diet changes, exercise and supplemental calcium and vitamin supplements, especially vitamin D. Following your diet regimen, as well as your medication plan and exercises everyday can keep you away from the harms of osteoporosis.

How should Fosamax (Alendronate) be taken?

You have to take Fosamax (Alendronate) as prescribed by your physician. Never take this drug in amounts smaller or larger than the amount prescribed. Also take this amount for the entire period set by your doctor for maximum effects. Follow the instruction given by your doctor in your prescription label.

Fosamax (Alendronate) tablets are normally taken once each day or once each week.

Take this drug first thing in the morning, upon waking up and at least 30 minutes before eating or drinking anything. If you are taking this drug on a weekly basis, make sure to take this drug at the same time and day of the week.

Take the drug with a full glass of water, preferably 6 to 8 ounces. Never use mineral water, juice, coffee or tea in taking this drug. Do not crush, chew or suck the tablet. It is recommended that the pill be swallowed whole.

After taking Fosamax (Alendronate), carefully make sure that the following things are done:
  • Do not lie down or recline for at least 30 minutes after taking this drug.
  • Never eat or drink anything 30 minutes after taking the drug, except plain water.
  • Do not take other medicines like vitamins and minerals, nutritional supplements, calcium, antacid and other prescription drugs for the first 30 minutes after taking the drug. It may be best to take other medicines at any other time of the day and be sure to talk to your doctor about the proper dosing schedules for other medicines you are supposed to take.

To make sure that you are responding ideally to the drug, you may be tested with a bone mineral density test (Bone Density Scan or DEXA) regularly. Visit your doctor regularly to have yourself examined.

If you are scheduled to have any dental work ups (especially surgical procedures), be sure to tell your physician and dentist ahead of time that you are taking Fosamax (Alendronate). You may have to pause from taking the drug for a short time.

Since Fosamax (Alendronate) is a treatment for Osteoporosis, it is important to consider that it is just a part of a group of treatment options, which among others include diet changes, exercise and supplemental calcium and vitamin supplements, especially vitamin D. Following your diet regimen, as well as your medication plan and exercises everyday can keep you away from the harms of osteoporosis.

Store this drug at a low moist and heat resistant area to avoid damage of the contents. Also keep this away from children’s reach.

Side effects of Fosamax (Alendronate)

Activate emergency medical help if you have any of these signs of an allergic reaction to Fosamax such as hives, difficulty of breathing, swelling of face, lips, tongue or throat. Refrain from using Fosamax and inform your physician if you have any of these serious side effects:
  • chest pain;
  • difficulty or pain when swallowing;
  • pain or burning under the ribs or in the back;
  • severe heartburn, burning pain in your upper stomach, or coughing up blood;
  • new or worsening heartburn;
  • fever, body aches, flu symptoms;
  • severe joint, bone, or muscle pain;
  • new or unusual pain in your thigh or hip;
  • jaw pain, numbness, or swelling.
Less serious Fosamax (Alendronate) side effects may include:
  • mild heartburn, bloating;
  • mild nausea, vomiting, or stomach pain;
  • diarrhea, gas, or constipation;
  • mild joint pain or swelling;
  • swelling in your hands or feet; or
  • dizziness, eye pain, headache.

These side effects listed are not complete and a variety of other side effects may present. Call your physician for medical advice about these side effects.

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