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Cytotec (Misoprostol)

Also known as: Arthrotec 
Misoprostol reduces stomach acid and replaces protective substances in the stomach that are inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin.
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Prescribing Information for Cytotec (Misoprostol):

What is Cytotec (Misoprostol)?

Cytotec is a medication used to reduce stomach acid and to restore the protective substances in the stomach that are suppressed by NSAIDs (nonsteroidal anti-inflammatory drugs) and aspirin.

The medication is commonly prescribed for prevention of stomach ulcer while using aspirin or an NSAID like nabumetone (Relafen), and fenoprofen (Nalfon), naproxen (Naprosyn, Aleve, Anaprox, Naprelan), diclofenac (Voltaren, Cataflam), ibuprofen (Motrin, Advil, Nuprin, others), oxaprozin (Daypro), indomethacin (Indocin), etodolac (Lodine), piroxicam (Feldene), ketoprofen (Orudis, Orudis KT, Oruvail), meloxicam (Mobic), tolmetin (Tolectin). NSAIDs and aspirin are used to treat inflammatory conditions, pain, fever, arthritis.

The medication can also be prescribed for other purposes.

The most important information about Cytotec (Misoprostol).

You should not use the medication to prevent the occurrence of ulcers in the stomach if you are pregnant or if you are planning pregnancy. In case if you become pregnant while using the medication, you should stop using it and call your doctor promptly. Cytotec (Misoprostol) is related to the FDA pregnancy category X. This signifies that it is dangerous for a fetus. Using this medication during pregnancy can lead to miscarriage or to unexpected abortion (which can be partial and cause severe bleeding requiring hospitalization and surgery), premature birth or birth defects. Misoprosol can also provoke uterine rupture in case of use after the 8th week of pregnancy, which can lead to dangerous bleeding, hysterectomy and/or death of the mother or the unborn baby. You will need to take a pregnancy test within 2 weeks since you start using Cytotec. The treatment will be started on the second or third day of your normal menstrual cycle. You will also need effective contraception to prevent pregnancy while you are using the medication and during one menstrual cycle after your treatment. Sometimes it is needed to use this medication under medical control for the induction of labor and delivery or abortion. Do not let anyone else take this medicine. It can be ineffective for other person and it would be dangerous if this person is pregnant.

How should Cytotec (Misoprostol) be used?

Follow the prescriptions of your doctor. If you need additional explanations ask your doctor, nurse, or pharmacist for them.

Take your dose of Cytotec (Misoprostol) with a full glass of liquid. It is commonly used 4 times a day with food and at bedtime. Follow the recommendations of your doctor.

Cytotec can provoke such side effects as mild or moderate diarrhea, stomach cramps, and/or nausea. These symptoms can occur within first several weeks of treatment and stop in about a week. If you use Cytotec (Misoprostol) with meal, the risk of these side effects can be minimized. Talk with your doctor if they do not stop after 8 days or if they are severe.

Do not stop using Cytotec earlier than prescribed. It is commonly used as long as you use NSAID or aspirin.

Do not let anyone else to take this medication. It can be ineffective for other person and it would be dangerous if this person is pregnant.

Keep Cytotec (Misoprostol) at room temperature protected from heat and moisture.

What side effects can Cytotec (Misoprostol) cause?

Seek emergency medical attention if you experience an allergic reaction to Cytotec (trouble breathing; hives; swelling of your face, lips, tongue, or throat).

Cytotec (Misoprostol) can provoke such side effects as stomach cramps, mild or moderate diarrhea, and/or nausea. These symptoms commonly occur within first several weeks of treatment and stop in about a week. If you use Cytotec with meal, the risk of these side effects can be minimized. Talk with your doctor if they do not stop after 8 days or if they are severe.

The medication can also cause less serious side effects. Do not stop using Cytotec (Misoprostol) if you have:
  • constipation;
  • headache;
  • vomiting;
  • menstrual cramps, spotting, or increased or irregular menstruation, or
  • flatulence.

Cytotec (Misoprostol) may also cause other side effects. Inform your healthcare provider if you have any painful or uncommon side effect.

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