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Arthritis

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Arthritis.

Arthritis is a group of autoimmune disorders, which involve different joints of the body and lead to damage of the joints. Involved joint/joints become inflamed and painful. The main presenting symptom of arthritis is generally joint pain and other joint problems, although symptoms (including presenting symptoms) may vary according to types of arthritis. Different types of arthritis may have different symptoms, for example deformity of fingers in rheumatoid arthritis, which is not generally seen in other types of arthritis, such as psoriatic arthritis.

The list of different types of arthritis is long and common types of arthritis are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, gouty arthritis, septic arthritis, arthritis secondary to other systemic diseases and many more. Osteoarthritis is the most common for of arthritis, which is due to degenerative changes in the involved joints due to wear and tear of joints. The most commonly involved joints in osteoarthritis are knee and ankle joints due to constant weight bearing.

What medications are available for treatment of arthritis?

The medications used in treatment may vary according to the type of arthritis. For example if arthritis is secondary to other disease, the primary disease also need to be treated along with arthritis. Treatment of arthritis involves treatment of symptoms of arthritis, such as pain and inhibition of progression of disease process.

The medications which are used for treatment of arthritis include NSAIDs (non-steroidal anti-inflammatory drugs, examples are ibuprofen, diclofenac, piroxicam etc.), glucocorticoids, DMARDs (disease modifying anti rheumatic drugs, examples are methotraxate, hydroxychloroquine, sulfasalazine etc.), Immunosuppressants (cyclosporine and cyclophosphamide), tumor necrosis factor inhibitors (etanercept, infliximab etc.) etc.

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