The inhalation with the medicine comes to the inner lining of the airways to begin to act. Due to this only 39% of dose of budesonide
is absorbed into the body and the absorbed budesonide contributes little to the effects on the airways.
The wide usage of budesonide in medicine.
The FDA approved the drug after conducting two studies with almost a 1000 of people involved. The study was held using randomized, placebo controlled and double-blind methods. The primary endpoint was induction of remission after 8 weeks of treatment. Remission was defined as a UCDAI score of <1. In both studies, Uceris 9 mg extended release tablets demonstrated superiority to placebo in inducing remission (p<0.025).
Budesonide is mainly produced as a capsule and it has to be taken by mouth. It is necessary to take it at the same time each day of the treatment course. It is much better to take the medicine it the morning. You should follow your doctor instructions and consult the prescription
very carefully. If something is still unclear to you, ask your doctor to help you. You should take capsules in the way it is directed. Never take more or less than it was prescribed
by your physician or pharmacist.
The capsule should be swallowed whole. It is very important to swallow it, but not to crush or chew.
The point is that budesonide does not cure the disease. It just helps to control the symptoms. In case the symptoms are controlled, your doctor can decrease your dose. If the symptom control lasts for more than three months, the doctor may stop treating you with this medicine. You are just to inform your doctor about how are you feeling and follow all of his instructions.