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02 Apr 2016 10:49 AM

Valacyclovir (Valtrex in the U.S.) is a medication prescribed in conditions of herpes (genital and herpes zoster) and cold sores or herpes labialis.


Valacyclovir (Valtrex in the U.S.) is a medication prescribed in conditions of herpes (genital and herpes zoster) and cold sores or herpes labialis. The drug doesn’t cure, it’s intended to prevent new focuses of disease from forming, to relieve itching and to heal sores.


The medication belong to nucleoside analogs, the class of drugs intended to mimic DNA building blocks. Valacyclovir prevents the formation of DNA viral cells, hence stops spreading of herpes infection the organism. Valacyclovir is a pro-drug, which doesn’t contain any active components. Human body converts it to acyclovirin is useful against the virus of herpes.



Special precautions


The drug may be also used in conditions of other illnesses. It’s contraindicated to use it not for herpes treatment before telling your doctor.


Before using tell your prescriber if you have allergies, or are allergic to acyclovir. Inform your doctor if you have any serious liver or kidneys diseases, immune system problems, especially acquired immunodeficiency syndrome or immunodeficiency virus (HIV or AIDS).



Tell your attending physician if you are going to combine the drug with any prescription or nonprescription medications, each of them may cause negative effects with valacyclovir.



It’s not adviced to use the drug if you are pregnant, planning the pregnancy or are breast-feeding. Take the drug with special care in the abovementioned cases, immediately get help if you notice some negative effects.



If you have hypersensitivity to any drugs contact you doctor and ask to order lab tests to check the possibility of taking the drug and the level of organism response. Despite the fact that herpes may be spread even if a person has no visual symptoms, it’s recommended to avoid sexual intercourse while curing herpes.



Valacyclovir side effects



Some categories of Valacyclovir side effects are denoted. If you notice breathing worsening, hives, allergic reactions like tongue, lips and throat swelling stop taking the drug and get medical help.


These side effects may cause bleeding and destroy red blood cells:

  • bloody vomiting or diarrhea

  • sudden fainting

  • yellowed or pale skin

  • not urinating

  • not related to the herpes skin irritations and spots


Less serious undesired effects of the drug are:

  • nausea

  • tired feeling and headache, depression

  • runny nose, sore throat

  • joint or stomach pain



Combination with other drugs



In high doses the medication may harm your liver and kidneys, moreover these undesired effects may be increased by other drugs that you combine with Valacyclovir.



It’s strongly recommended to tell the physician if you take:



  • cancer drugs e.g. streptozocin, oxaliplatin, cisplatin, ifosfamide, proleukin, gliadel

  • lithium

  • drugs used to prevent rejection of transplant organs e.g. tacrlimus and sirolimus

  • methotrexate

  • any antiviral medications or antibiotics

  • drugs prescribed in conditions of ulcerative colitis

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