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19 Feb 2012 06:16 AM

Ibuprofen – A Popular NSAID Available Readily


It is necessary to understand in brief about non-steroidal anti-inflammatory drugs before we proceed further about Ibuprofen as it also belongs to a class of NSAID’s itself. We all are aware about the presence and role of Prostaglandins in our body. These belong to a family of chemicals that are responsible for inflammation, fever and pain on our body. It’s a way of our immune system to combat infections by secretion of various types of chemicals one of them which is prostaglandins. These are also responsible for aiding platelets in activity for clotting of blood. Ibuprofen is the generic name for the popular medicine that is sold under the brand name of Motrin. These pills act on the enzymes cyclooxygenase1 and 2, resulting in lower production of prostaglandins and thus reducing inflammation and related symptoms. Excessive use of NSAID’s is not encouraged as prostaglandins also protect the lining of stomach which gradually gets reduced due to uptake of Ibuprofen and similar drugs leading to ulceration of the stomach and intestinal lining.
Preparation of the tablets is in 200, 400, 600 and 800 mg strength. Motrin [ibuprofen] is also available in chewable tablet form which is easy to take when it is difficult for the patient to swallow. Oral drops and suspension for children are also available in pharmacy stores.
In most of the infections or diseases the preliminary symptoms are fever pains and aches such as headache, body ache fatigue etc. the common dosing for these is between 200 or 400 mg with a gap of 4 to 6 hours. Arthritic pain can also be kept under control but with a different dosage as decided by the physician.
Children who are 6 months up to the age of 12 years are given low doses and generally calculation depends upon their body weight. Motrin must be given along with meals as it will prevent stomach upset.
Ibuprofen is a common drug that is used by a huge population on a regular basis. But its use must be limited and especially if you are on medication for blood pressure or other drugs. Motrin has been associated with other medications for drug to drug interactions resulting in inefficacy of both or one of the drugs. Lithium if present in excess levels in our blood may cause toxicity. Ibuprofen along with aminoglycosides can lead to reduced elimination of aminoglycosides from the body causing its adverse effects if used for prolonged periods.Motrin [Ibuprofen] must not be taken if other blood thinner such as warfarin is being currently prescribed to a patient. If need arise a physician must be consulted before administering any further new drugs. Pregnant women must not take this drug as it can lead to side effects to the unborn child. Medical reports and clinical studies suggest that women who are breastfeeding pose little risk to the newborn child with Motrin.Ibuprofen does not get secreted in the breast milk so nursing mothers can take this medicine under supervision of their gynecologist or physician.
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