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14 Feb 2012 02:14 PM

Amitriptyline (Elavil) - An antidepressant


Amitriptyline (Elavil) is tricyclic anti depressant. It is most widely used tricyclic anti depressant. It reduces depressive symptoms and also eases tension headaches, some schizophrenic symptoms, anxiety attacks and migraines. Depression is pervasive sense of gloom and sadness. Amitriptyline (Elavil) elevates the mood by raising level of the neurotransmitters in the nerves of brain. In May 1983 Food and Drug Association approved Amitriptyline (Elavil).
Amitriptyline (Elavil) is used for elevating the mood of depressed patients. It is used for many medical conditions like depressive disorders, attention deficit hyperactivity disorder, anxiety disorder, migraine prophylaxis, and bipolar disorder, eating disorders, insomnia and post herpetic neuralgia. Amitriptyline (Elavil) is used in the ankylosing spondylitis for relieving pain. It is used as preventive for patients having recurring biliary dyskinesia. Amitriptyline (Elavil) is used in children for treating nocturnal enuresis. It may be prescribed in medical conditions like post traumatic stress disorder, chronic cough, tinnitus, chronic pain, fibromyalgia, vulvodynia, chronic fatigue syndrome, interstitial cystitis, neurological pain, laryngeal sensory neuropathy, painful paresthesias which are related to the multiple sclerosis. The randomized controlled trial which was published in 2005 (June), found that the Amitriptyline (Elavil) was effective in the functional dyspepsia.
Amitriptyline (Elavil) can be taken with food or without food. The recommended dose of Amitriptyline (Elavil) for adults is 40 mg to 150 mg per day in divided doses. Lowest effective dose of Amitriptyline should be used. If you miss any dose take it when you remember, but if it is near to time of next dose, skip missed dose and continue with regular dose. Do not double dose to match up missed dose. After the symptoms improve, dose of Amitriptyline (Elavil) can be reduced to lowest amount which will relieve symptoms.
Amitriptyline is not supposed to use with the monoamine oxidase inhibiting medicines. Convulsions, high fever and even death may occur when these medicines are used together. Epinephrine is not supposed to use with Amitriptyline (Elavil) as together they may cause very high blood pressure. Alcohol blocks antidepressant action of the Amitriptyline and increases Amitriptyline’s sedative effect. Cimetidine may increase amitriptyline blood levels and side effects of Amitriptyline. Effects of this treatment in pregnancy are not established. Amitriptyline (Elavil) passes in breast milk and may cause adverse effects in nursing infant.
If you are allergic to Amitriptyline do not take this drug before consulting with your doctor. If you are taking MAO inhibitor (like tranylcypromine, phenelzine) tell your doctor before starting this treatment. Some troublesome side effects of Amitriptyline (Elavil) include blurred vision, fast heart rate, urinary retention, constipation, dry mouth, weight loss, weight gain and low blood pressure. Some rare side effects of this drug are hives, rash, hepatitis and seizures. Amitriptyline (Elavil) is used with care in patients having seizures as it can increase risk of the seizures. Amitriptyline (Elavil) can cause the elevated pressure in eyes of some patients having glaucoma. If this treatment is stopped abruptly headache, restlessness, dizziness and nausea may occur. Withdrawal symptoms can occur when few doses of Amitriptyline (Elavil) are missed. Dose should be reduced gradually for stopping treatment.
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